| Item Type | Name |
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Concept
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Antigen-Presenting Cells
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Concept
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Adenosine Triphosphatases
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Concept
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Bone Marrow Cells
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Concept
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Cell Communication
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Concept
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Cell Line, Transformed
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Concept
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Cell Count
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Concept
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Cell Differentiation
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Concept
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Cell Nucleus
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Concept
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Cell Membrane
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Concept
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Cell Division
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Concept
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Clone Cells
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Concept
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Immune Tolerance
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Concept
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Fluorescent Antibody Technique
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Concept
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Mice, Transgenic
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Concept
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Models, Theoretical
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Concept
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Granulation Tissue
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Concept
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Hybrid Cells
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Concept
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Receptors, Cell Surface
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Concept
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Receptors, Antigen, B-Cell
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Concept
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Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
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Concept
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Bone Marrow Transplantation
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Concept
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Time Factors
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Concept
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Transcription, Genetic
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Concept
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Stem Cells
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Concept
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Thermolysin
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Concept
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Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor
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Concept
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Tumor Cells, Cultured
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Concept
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CD4-Positive T-Lymphocytes
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Concept
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Protein Structure, Tertiary
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Concept
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Receptors, Antigen, T-Cell, alpha-beta
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Concept
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Self Tolerance
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Concept
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Transgenes
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Concept
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Epitopes, T-Lymphocyte
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Concept
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Jurkat Cells
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Concept
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Adoptive Transfer
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Concept
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Precipitin Tests
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Concept
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Real-Time Polymerase Chain Reaction
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Concept
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Central Tolerance
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Concept
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Trypsin
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Concept
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Precursor Cells, B-Lymphoid
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Concept
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Transfection
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Concept
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Imaging, Three-Dimensional
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Concept
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Endothelial Cells
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Concept
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Thymocytes
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Concept
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Cell Line, Tumor
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Concept
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Cell Line
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Concept
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Immunologic Techniques
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Concept
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Receptors, Antigen, T-Cell
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Concept
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T-Lymphocytes
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Concept
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Translocation, Genetic
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Concept
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Signal Transduction
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Concept
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Coculture Techniques
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Concept
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Quantitative Trait Loci
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Concept
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Microscopy, Electron, Transmission
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Academic Article
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Receptor editing: an approach by autoreactive B cells to escape tolerance.
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Academic Article
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Editing disease-associated autoantibodies.
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Academic Article
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A Shannon entropy analysis of immunoglobulin and T cell receptor.
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Academic Article
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A disease-related rheumatoid factor autoantibody is not tolerized in a normal mouse: implications for the origins of autoantibodies in autoimmune disease.
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Academic Article
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Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing.
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Academic Article
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A solution to the rheumatoid factor paradox: pathologic rheumatoid factors can be tolerized by competition with natural rheumatoid factors.
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Academic Article
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Clone: a Monte-Carlo computer simulation of B cell clonal expansion, somatic mutation, and antigen-driven selection.
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Academic Article
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Somatic mutation and light chain rearrangement generate autoimmunity in anti-single-stranded DNA transgenic MRL/lpr mice.
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Academic Article
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Revising B cell receptors.
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Academic Article
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Regulation of anti-DNA B cells in recombination-activating gene-deficient mice.
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Academic Article
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Chronic graft-versus-host in Ig knockin transgenic mice abrogates B cell tolerance in anti-double-stranded DNA B cells.
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Academic Article
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Autoreactive B cells in the marginal zone that express dual receptors.
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Academic Article
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Structural basis for autoantibody recognition of phosphatidylserine-beta 2 glycoprotein I and apoptotic cells.
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Academic Article
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Regulation of anti-phosphatidylserine antibodies.
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Academic Article
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Analysis of B cell receptor production and rearrangement. Part I. Light chain rearrangement.
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Academic Article
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Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice.
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Academic Article
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Influence of a V kappa 8 L chain transgene on endogenous rearrangements and the immune response to the HA(Sb) determinant on influenza virus.
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Academic Article
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Dynamical analysis of a degenerate primary and secondary humoral immune response.
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Academic Article
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Anti-DNA B cells in MRL/lpr mice show altered differentiation and editing pattern.
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Academic Article
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Editors and editing of anti-DNA receptors.
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Academic Article
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Secondary heavy chain rearrangement: a mechanism for generating anti-double-stranded DNA B cells.
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Academic Article
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T-cell epitope repertoire as predicted from human and viral genomes.
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Academic Article
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Ig H and L chain contributions to autoimmune specificities.
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Academic Article
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Control of genotypic allelic inclusion through TCR surface expression.
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Academic Article
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Development and selection of edited B cells in B6.56R mice.
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Academic Article
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Selection of anti-double-stranded DNA B cells in autoimmune MRL-lpr/lpr mice.
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Academic Article
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Light chain editing generates polyreactive antibodies in chronic graft-versus-host reaction.
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Academic Article
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Pillars article: generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin. Proc. Natl. Acad. Sci. USA, 81: 3180-3184, May 1984.
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Academic Article
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Editing anti-DNA B cells by Vlambdax.
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Academic Article
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Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation.
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Academic Article
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In-silico cell surface modeling reveals mechanism for initial steps of B-cell receptor signal transduction.
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Academic Article
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Heavy-chain class switch does not terminate somatic mutation.
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Academic Article
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Consequences of receptor editing at the lambda locus: multireactivity and light chain secretion.
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Academic Article
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Selection of individual VH genes occurs at the pro-B to pre-B cell transition.
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Academic Article
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Interspersion of the VHQ52 and VH7183 gene families in the NFS/N mouse.
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Academic Article
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Alternative mechanisms of receptor editing in autoreactive B cells.
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Academic Article
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Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma.
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Academic Article
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Deletion and editing of B cells that express antibodies to DNA.
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Academic Article
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Model for competition from self during passive immunization, with application to broadly neutralizing antibodies for HIV.
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Academic Article
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Receptor editing: an approach by autoreactive B cells to escape tolerance. The Journal of Experimental Medicine. 1993. 177: 999-1008.
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Academic Article
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Intra-Golgi formation of IgM-glycosaminoglycan complexes promotes Ig deposition.
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Academic Article
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The role of clonal selection and somatic mutation in autoimmunity.
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Academic Article
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How immunoglobulin V kappa genes rearrange.
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Academic Article
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Consideration of the transgenic and other approaches to studying DNA antibodies and their idiotypes.
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Academic Article
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Light chain editing in kappa-deficient animals: a potential mechanism of B cell tolerance.
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Academic Article
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Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). A structural explanation for the high frequency of IgM anti-IgG B cells.
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Academic Article
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A complex translocation at the murine kappa light-chain locus.
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Academic Article
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Chromosomal locations of mouse immunoglobulin genes.
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Academic Article
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Plasmacytomas of the NZB mouse.
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Academic Article
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Reorganization and expression of immunoglobulin genes: status of allelic elements.
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Academic Article
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Transcription of the unrearranged mouse C kappa locus: sequence of the initiation region and comparison of activity with a rearranged V kappa-C kappa gene.
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Academic Article
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B cell receptor light chain repertoires show signs of selection with differences between groups of healthy individuals and SLE patients.
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Academic Article
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Constitutive secretion of transgene-encoded IgG2b autoantibodies leads to symptoms of autoimmune disease.
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Academic Article
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The joining of V and J gene segments creates antibody diversity.
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Academic Article
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An isotype switched and somatically mutated rheumatoid factor clone isolated from a MRL-lpr/lpr mouse exhibits limited intraclonal affinity maturation.
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Academic Article
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Editing and escape from editing in anti-DNA B cells.
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Academic Article
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Origins of anti-DNA antibodies and their implications for B-cell tolerance.
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Academic Article
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Analysis of VH gene replacement events in a B cell lymphoma.
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Academic Article
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B lymphocytes may escape tolerance by revising their antigen receptors.
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Academic Article
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Transcription of mouse kappa chain genes: implications for allelic exclusion.
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Academic Article
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Light chain contribution to specificity in anti-DNA antibodies.
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Academic Article
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The site and stage of anti-DNA B-cell deletion.
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Academic Article
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Lupus susceptibility genes may breach tolerance to DNA by impairing receptor editing of nuclear antigen-reactive B cells.
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Academic Article
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Apoptotic marginal zone deletion of anti-Sm/ribonucleoprotein B cells.
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Academic Article
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Aberrant rearrangement of the kappa light-chain locus involving the heavy-chain locus and chromosome 15 in a mouse plasmacytoma.
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Academic Article
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DNA between variable and joining gene segments of immunoglobulin kappa light chain is frequently retained in cells that rearrange the kappa locus.
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Academic Article
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The mechanism of autoantibody production in an autoimmune MRL/lpr mouse.
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Academic Article
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A rheumatoid factor transgenic mouse model of autoantibody regulation.
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Academic Article
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Immunochemical studies on mouse myeloma proteins with specificity for dextran or for levan.
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Academic Article
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Mouse lambda-chain sequences.
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Academic Article
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Fixing mismatches.
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Academic Article
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Reflections on the clonal-selection theory.
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Academic Article
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Objective quality evaluation of fluorescence images to optimize automatic image acquisition.
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Academic Article
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Automatic analysis of immunofluorescence patterns of HEp-2 cells.
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Academic Article
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Antibodies that bind complex glycosaminoglycans accumulate in the Golgi.
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Academic Article
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Sumoylated HSP90 is a dominantly inherited plasma cell dyscrasias risk factor.
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Academic Article
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Light chain editors of anti-DNA receptors in human B cells.
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Academic Article
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ClearVolume: open-source live 3D visualization for light-sheet microscopy.
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Academic Article
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A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.
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Academic Article
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Sumoylated HSP90 is a dominantly inherited plasma cell dyscrasias risk factor.
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Academic Article
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Two- and three-dimensional co-culture models of soft tissue healing: pericyte-endothelial cell interaction.
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Academic Article
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Self-Antigen-Driven Thymic B Cell Class Switching Promotes T Cell Central Tolerance.
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Academic Article
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LAPTM5 mediates immature B cell apoptosis and B cell tolerance by regulating the WWP2-PTEN-AKT pathway.
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Academic Article
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MarrowQuant 2.0: A Digital Pathology Workflow Assisting Bone Marrow Evaluation in Experimental and Clinical Hematology.
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Concept
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In Vitro Techniques
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Grant
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Receptor editing, Autoimmunity and Free Light Chain Pro*
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Grant
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GENETIC CONTROL OF AUTOIMMUNITY
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Grant
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Genetics and Regulation of Autoantibodies
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